Wednesday, July 16, 2014

Some pediatrician comments on the 'new' DTwP Quinvaxem that is supposed to be less painful than regular DPT vaccines in India

The following is from a discussion group in the IAP Adolescent Chapter talking about QUINVAXEM - the latest controversial Novartis vaccine of DTwP that is being touted as being relatively 'painless'. 
Apologies that you have to read the conversation in reverse order, the latest comments are on the top while the original query is at the bottom ...
I have removed the names of the participant pediatricians, except mine


"
From: xxxx@gmail.com>

Dear sir, 
SAGE recommendations regarding the use of dtap has not changed. Pertussis resurgence is not a global phenomenon. 
Regarding the number of components in dtap will not change the efficacy vaccine as far as immediate protection from disease. IAPCOI has to clarify this thing. 
Dtwp and Dtap differ slightly in duration of protection against pertussis.
In the private practice continuing dtap may not effect the epidemiology in India
as long as we continue dtwp in our national immunisation programme which covers almost 90% immunisation in India. 
Iacopi may clarify the issue.

With regards, 
Dr. xxxxxx
EB member CIAP 2014.


From: xxxxxx@rediffmail.com>

Sir
I have read SAGE paper and found that they have maintained status quo rather than? recommending switching to whole cell vaccine.
SAGE recommendations are for public sector? and not for private sector where you can maintain status quo.
We were always taught that in private practice it is the safety which is of utmost importance even at the cost of reduced efficacy.
IAPCOI is a body to recommend immunisation practices for private sector only and hence should focus on these legitimate concerns of us the private practitioners. 
how much percentage of pediatric population is being catered by private sector so that by exposing them to acellular vaccine would cause any shift in epidemiology of the disease is a legitimate concern IAPCOI should investigate and answer.
I hope to get a good discussion on this. 
Dr xxxxxx
Kanpur


Sent from RediffmailNG on Android

From: drtuteja@adolesenceindia.com
Sent:Mon, 26 May 2014 19:14:20 +0530
To: xxxxxx@rediffmail.com
Subject: Re: [AdolesenceIndia] Whole cell pertussis vaccine claims to be less painful
Untitled Document
From: xxxxxx@gmail.com>
> 

Well said dr Gupta. Many want to postpone it, till pentaxim is available

On 14 May 2014 22:35, wrote:

> 
From: Gaurav Gupta
> 

I have a slightly different take,?
The expectations of parents have changed - especially in the private sector.
Many parents do NOT want any significant fever pain swelling or crying episodes, and I do get calls from parents regarding these local side-effects on a regular basis.?
I believe that this is something like cars/ air conditioners/ fast internet/ cable TV etc. When we did not have these modern amenities, we were happy without them, but now we believe that every car should have AC, and everyone should have fast internet access, and the latest mobile phone too.
Similarly, less pain/ swelling/ fever in a vaccine is considered to be a positive thing with both parents working and not able to manage a fussy irritable child especially through the night, when they have to work the next day.
This is the reason that like the West, DTaP has a role to play in our setting too, albeit in a limited way. A large majority will still get DTwP which may be a slightly superior vaccine, but some would still want lesser side-effects, and if we have a choice - I believe they should get what they want, with appropriate counseling.
Regards
Dr Gaurav Gupta, Mohali

> 
> 
On Tue, May 6, 2014 at 6:11 PM, wrote:
> 

> 
From: xxxxxx@gmail.com>
> 

well said kapse sir.since the time i joined the govt service in1979 and till my retirement in 2010 I had used, and even today in govt sector they still use it without any problem
xxxxxx Tamilnadu

> 
> 
On Thu, Apr 24, 2014 at 6:01 PM, wrote:
> 

> 
From: xxxxxx@gmail.com>
> 

It was around 1973 (I was doing PG) when DPT was introduced, we excusively used this vaccine till around 2000 without great problems.

Today also 80% of children receive DTwP (govt sector) without much problems.

I do not understand why should we get carried away with these grossly exaggareted reactogenecity claims.
> xxxxxx
> 

On 13 Apr 2014 10:21, wrote:

> 
From:xxxxxx@hotmail.com>
> 

Rightly clarified by Dr Gaurav Gupta.?
Here the debate was about claim by company about their product being less reactogenic then acellular DTP combo vaccine. Ofcourse the prize is almost 4 times for whole cell DPT pentavalent combo vaccine.
>xxxxxx
Surat,Gujarat


>--Forwarded Message Attachment--
> 
> From: Gaurav Gupta
> 
> 
Dear Dr xxxxxx,
Just to clarify, Quinvaxem is a combination vaccine, and should be compared against a pentavalent vaccine like Easy five  pentavac, not DTwP alone. Of course it is still unreasonably priced as compared to these, but I wanted to allow for the correct comparison,
Regards
Dr Gaurav Gupta,?
Chandigarh

> 
> 
On Sun, Mar 30, 2014 at 10:30 AM, wrote:
> 

> 
From: Dr. xxxxxx@hotmail.com>
> 
Dear Drxxxxxx,
The cost of DTwP by NOVARTIS is around 1500 Rs. So it is more then 120 times greater then DPT by serum.?
This is just for your information.?
> Dr. xxxxxx
>Surat,Gujarat

> 
> 
To: xxxxxx@hotmail.com
>Subject: Re: Fwd: [AdolesenceIndia] Whole cell pertussis vaccine claims to be less painful
>From: drtuteja@adolesenceindia.com
> Date: Wed, 26 Mar 2014 17:15:37 -0500
> 
> From: xxxxxx@gmail.com>
> 
> 
"Loot sake to loot"
> Jas become the motto of vaccine industry today.

The word PAINLESS is misnomer no injection could ever be painless, playong on parents psyche they earleir had pushed inferior quality vaccine now they wish to push an exorbitant product.

Unfortunately we too are driven by greed therefore can not resist whole heartedly.

Dr xxxxxx

On 25 Mar 2014 21:05, wrote:
> 

> 
From:
> 
> 

> 
>Sent from my iPad

>Begin forwarded message:
> 
> 
From: xxxxx@yahoo.co.in>
>Date: 24 March 2014 15:35:42 IST
>To: AdolesenceIndia@yahoogroups.co.in
> Subject: Re: [AdolesenceIndia] Whole cell pertussis vaccine claims to be less painful
>Reply-To: AdolesenceIndia@yahoogroups.co.in
> 
?

> 
sir the cost of liquid pentavalent (NOVARTIS)is twice that of normal one
xxxxx ,trichy,TN

> 
On Monday, 24 March 2014 2:59 PM, Dr. Digant Shastri wrote:
> 
?
Dear?xxxxx,
Such claims are not evidence based. When the MR of Novartis claimed such before me i asked for scientific evidence and prove it. He didn't turned up then. More over i also searched the litrature including pubmed but could not find and such study. So this is baseless claim , doctors should not get carried out by such claim without evidence. I presume that such false claim may be such to justify their exorbitant cost difference- if i am not wrong 120 times more then DPwP from indigenous manufacturer.
with regards

>xxxxx

> 
> 
From: xxxxx@yahoo.com
> To: AdolesenceIndia@yahoogroups.co.in
>Date: Sun, 23 Mar 2014 09:05:01 -0700
>Subject: Re: [AdolesenceIndia] Whole cell pertussis vaccine claims to be less painful
> ?

> 
Dear all
Greetings fro Welcome to AdolesenceIndia Community
Requesting to all concern  who are ?experts ?in vaccinology to respond and comment?
Best wishes
?
?
?
Sincerly
Best wishes  regards.
Dr . J . S. Tuteja
MD.DCH.PGD-AP.F.I.A.P.
Chairperson:
Adolescent Health Academy.IAP2012-2013
2014-2015
MKU 2013?????????????????????????????????????????????????? 
> Owner  moderator
www.adolesenceindia.com
Requesting ?mail to
drtuteja@adolesenceindia.com
Contact:.09752068649-,09893321030
Batte gira deti hai-Faslon kee diwaree.
???????????????????????????????

> 
On Sunday, March 23, 2014 9:27 PM, xxxxx@gmail.com> wrote:
> 
?
[Attachment(s) from rajendra makuluri included below]

Dear friends
A liquid pentavalent DTwP vaccine by? Novartis is claimed to be less painful. Comments please. 
Dr. xxxxx

> 
> 

> 

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